CARIVALAN Carvedilol 25 mg+ Ivabradine hydrochloride 5mg 1 Film-Coated Tablet (sold per piece) [PRESCRIPTION REQUIRED]
Indicated as substitution therapy in adult patients with normal sinus rhythm already controlled by ivabradine and carvedilol taken concomitantly at the same dose levels for:
- the symptomatic treatment of chronic stable angina pectoris in coronary artery disease patients,
- the treatment of chronic heart failure (II-IV NYHA-class) with systolic dysfunction.
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Place of Origin
Oral use. One tablet twice daily, once in the morning and once in the evening during meal.
Should only be used in patients controlled on stable doses of the individual components given concurrently when carvedilol and ivabradine are at the optimal dose.
The fixed dose combination is not suitable for initiation therapy.
If required, titration should be done with the individual components, and recommended to take place with the availability of serial heart measurements, ECG or ambulatory 24-hour monitoring.
Caution in patients with creatinine clearance below 15 mL/min, in moderate hepatic impairment and in elderly.
Monitor renal function in chronic heart failure patients with SBP less than 100 mmHg.
Contraindicated in severe hepatic impairment.
White, octagonal, film-coated tablet (diameter 7.8 mm) engraved with CI6 on one face and on the other face.
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