REMINDER: A doctor’s prescription is required to purchase this product. To avoid delay in delivery or cancellation of your order (before the item is SHIPPED); please email a copy of your prescription (.jpeg or .pdf file format) to OnlinePharmacy@watsons.com.ph with your order number after Checkout. Our pharmacist will also get in touch with you to validate your prescription. Please be ready to show your original prescription upon claiming/delivery of your order.
DOSAGE AND ADMINISTRATIONS: Duodenal ulcer Usually, for adults, a daily oral dose of 30mg of Lansoprazole is administered once a day for 4-6 weeks. Gastric ulcer, stomal ulcer, reflux esophagitis and Zollinger-Ellison syndrome Usually, for adults, a daily oral dose of 30mg of Lansoprazole is administered once a day up to 8 weeks. Pediatric (1 to 11 years of age) Short-Term Treatment of Symptomatic GERD, Short-Term Treatment of Erosive Esophagitis - < 30 kg --- 15mg once daily for up to 12 weeks > 30 kg --- 30mg once daily for up to 12 weeks (12 to 17 years of age) Short-Term Treatment of Symptomatic GERD Non-erosive GERD 15mg --- once daily for up to 8 weeks Erosive esophagitis 30mg --- once daily for up to 8 weeks For the maintenance therapy of reflux esophagitis and duodenal ulcers, for elderly patients and for patients with impaired hepatic function, 15mg Lansoprazole is orally administered once daily. The recommended doses for Lansoprazole-containing regimens for Helicobacter pylori eradication in patients with duodenal ulcer and gastric ulcer are 30mg Lansoprazole twice daily plus two of the following antibiotics for seven (7) days – clarithromycin 250 mg twice daily, amoxicillin 1g twice daily or metronidazole 500mg twice daily.
CONTRAINDICATION: Lansoprazole (Prevacid) Tablets are contraindicated in the following patients: Patients with a history of hypersensitivity to any of the ingredients of this drug. Patients who are receiving atazanavir sulfate or rilpivirine hydrochloride
PRECAUTIONS: 1. Careful Administration ?(Lansoprazole (Prevacid FDT) should be administered with care in the following patients)?? (1) Patients with a history of drug hypersensitivity. (2) Patients with hepatic disorders ?A delay in the metabolism and excretion of Lansoprazole (Prevacid FDT) may occur?? (3) Elderly patients (See 5. Use in Elderly) 2. Important Precautions (1) At the treatment, the course of the disease should be closely observed and the minimum therapeutic necessity should be used according to the disease condition. (2) For the treatment of gastric ulcer, duodenal ulcer and stomal ulcer, it is advisable not to use this drug for maintenance therapy because there has not been enough experience in long term use. (3) In the maintenance of healing reflux esophagitis, Lansoprazole (Prevacid FDT) can be administered only to the patients who repeat recurrence and recrudescence of the condition. Administration to the patients who do not necessitate maintenance of healing should be avoided. When the healing is maintained over a long period by once daily administration of 30mg or 15mg, and when there is no risk of recurrence resulting from dose reduction or discontinuation of administration, the dose should be reduced to a daily dose of 15mg, or administration should be discontinued. Careful observation by such means as periodic endoscopy is recommended during the maintenance of healing. (4) In the treatment of nonerosive gastroesophageal reflux disease, effect of Lansoprazole (Prevacid FDT) should be checked about 2 weeks after the start of this drug. If no improvement is observed in the symptoms, causes other than acid reflux are conceivable. Therefore, such consideration as the change to more appropriate treatment should be made. (5) In the treatment of nonerosive gastroesophageal reflux disease, Lansoprazole (Prevacid FDT) should be administered after repeats (2 or more days in a week) of acid reflux symptoms such as heartburn and acid belching are confirmed on inquiry. The administration of Lansoprazole (Prevacid FDT) may mask the symptoms of a malignant tumor such as gastric/esophageal cancer or of other gastrointestinal disorders. It is, therefore, necessary to ascertain that no such diseases are present on endoscopy etc. (6) When Lansoprazole (Prevacid FDT) is used as an adjunct for Helicobacter pylori eradication, precautions such as contraindications, careful administration and clinically significant adverse reactions listed in the package inserts of the other drugs in the eradication should be rechecked without fail. (7) Daily treatment with any acid-suppressing medications over a long period of time (e.g. longer than three years) may lead to malabsorption of cyanocobalamin (Vitamin B12) caused by hypo- or achlorhydria. Rare reports of cyanocobalamin deficiency occurring with acid-suppressing therapy have been reported in the literature. This diagnosis should be considered if clinical symptoms consistent with cyanocobalamin deficiency are observed. (8) Increased Chromogranin A (CgA) level may interfere with investigations for neuroendocrine tumors. To avoid this interference, Prevacid FDT treatment should be stopped for at least 5 days before CgA measurements. If CgA and gastrin levels have not returned to reference range after initial measurement, measurements should be repeated 14 days after cessation of proton pump inhibitor.
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