REMINDER: A doctor’s prescription is required to purchase this product. To avoid delay in delivery or cancellation of your order (before the item is SHIPPED); please email a copy of your prescription (.jpeg or .pdf file format) to OnlinePharmacy@smwatsons.comwith your order number after Checkout. Our pharmacist will also get in touch with you to validate your prescription. Please be ready to show your original prescription upon claiming/delivery of your order.
Add-on therapy for the symptomatic treatment of stable angina pectoris in adults who are inadequately controlled or intolerant to 1st-line anti-anginal therapies (eg β-blockers &/or Ca antagonists).
Place of Origin
May be taken with or without food: Swallow whole; do not break/chew/crush.
Increased plasma conc w/ inhibitors of CYP3A4 (eg; itraconazole; ketoconazole; voriconazole; posaconazole; HIV PIs; clarithromycin; telithromycin; nefazodone; grapefruit juice; diltiazem; erythromycin; fluconazole); P-gp (eg; ciclosporin; verapamil) & CYP2D6 (eg; paroxetine) inhibitors. Decreased steady-state conc w/ CYP3A4 inducers (eg; rifampicin; phenytoin; phenobarb; carbamazepine; St. John's wort). Increased plasma conc of P-gp or CYP3A4 [eg; simvastatin (limit the dose of simvastatin to 20 mg once daily in patients taking Ranexa); lovastatin; atorvastatin; ciclosporin; tacrolimus; sirolimus; everolimus] substrate; digoxin. Increased exposure to metoprolol or other CYP2D6 substrates (eg; propafenone & flecainide or to a lesser extent; TCAs & antipsychotics); metformin & other OCT2 substrates (eg; pindolol & varenicline). CYP2B6 substrates (eg; bupropion; efavirenz; cyclophosphamide). Increased possible risk of ventricular arrhythmias w/ antihistamines (eg; terfenadine; astemizole; mizolastine); antiarrhythmics (eg; quinidine; disopyramide; procainamide); erythromycin & TCAs (eg; imipramine; doxepin; amitriptyline).
Each tablet contains 500 mg of Ranolazine.
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