Ribociclib 200mg 1 Tablet
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KRYXANA Ribociclib 200mg 1 Tablet
Ribociclib (Kryxana?) is (a cyclin-dependent kinase inhibitor, CDKi) indicated for the treatment of patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2) negative (locally) advanced or metastatic breast cancer in combination with an aromatase inhibitor or fulvestrant.
In pre or peri-menopausal women, the endocrine therapy should be combined with a luteinizing hormone-releasing hormone (LHRH) agonist.
The recommended dose is 600 mg (3 x 200 mg film-coated tablets) taken orally, once daily for 21 consecutive days followed by 7 days off treatment resulting in a complete cycle of 28 days. Ribociclib can be taken with or without food (see section INTERACTIONS).
Active Substance: Ribociclib Excipients: Tablet core Microcrystalline cellulose, low-substituted hydroxypropylcellulose, crospovidone (Type A), colloidal silicon dioxide, magnesium stearate., Coating material: Polyvinyl alcohol (partially hydrolysed), titanium dioxide (E171), iron oxide black (E172), iron oxide red (E172), talc: lecithin (soy) (E322), xanthan gum.
Ribociclib is contraindicated in patients with hypersensitivity to the active substance
Product Code: 50028720