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XELJANZ Tofacitinib 11mg 1 tablet
Treatment of adult patients with moderately to severely active rheumatoid arthritis (RA), who have had an inadequate response to one or more disease-modifying anti-rheumatic drug (DMARDs).
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Tofacitinib (Xeljanz/Xeljanz XR) has not been studied and use should be avoided in combination with TNF antagonists, IL-1R antagonists, IL-6R antagonists, anti-CD20 monoclonal antibodies, IL-17 antagonists, IL-12/IL23 antagonists, anti-integrins, and selective co-stimulation modulators and potent immunosuppressants, such as azathioprine, cyclosporine, and tacrolimus because of the possibility of increased immunosuppression and increased risk of infection. Tofacitinib (Xeljanz/Xeljanz XR) treatment should be interrupted if a patient develops a serious infection until the infection is controlled.It is given orally with or without food.
Special Warnings and Precaution for Use: Tofacitinib (Xeljanz/Xeljanz XR) should not be initiated in patients with an active infection