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It is used to reduce LDL-cholesterol, Apolipoprotein B, and triglycerides, and to increase HDL-cholesterol in the treatment of hyperlipidaemias, including hypercholesterolaemias and combined (mixed) hyperlipidaemia (Type IIa or IIb hyperlipoproteinaemias), hypertriglyceridaemia (Type IV), and dysbetalipoproteinaemia (Type III) and also can be effective as adjunct therapy in patients with homozygous familial hyper-cholesterolaemia who have some LDL-receptor function.
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The usual dose is 10 mg to 20 mg of Atorvastatin once daily. Initial dose of 40 mg daily may be used in patients who require a large reduction in LDL-cholesterol. The dose may be adjusted at intervals of 4 weeks up to a maximum of 80 mg daily.
Atorvastatin (as Calcium) 40mg
It should not be given to patients with acute liver disease or unexplained persistently raised serum-aminotransferase concentrations.