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Indicated for the treatment of Pulmonary Arterial Hypertension, to improve exercise ability and to decrease clinical worsening.
Place of Origin
Pulmonary HTN â‰¥12 yrs
Bosentan (as monohydrate) 125mg
Contraindications: Moderate-severe hepatic impairment (Child-Pugh Class B or C).
Special Precautions: Liver-aminotransferase concentrations should be measured before starting therapy