Transplantation Indication:Prevention of graft rejection following kidney, liver, heart, combined heart-lung, lung or pancreas allogeneic transplantations, Treatment of transplant rejection in patients previously receiving other immunosuppressive agents. Prevention of graft rejection following bone marrow transplantation, Prevention or treatment of graft-versus-host disease (GVHD). Non-Transplantation Indications: Treatment of active sight-threatening intermediate or posterior uveitis of non-infectious aetiology in patients where conventional therapy fails, or causes unacceptable side effects, Treatment of Behcet uveitis with repeated inflammatory attacks involving the retina. Sandimmun Neoral can be used to induce and maintain remissions. It can also be used to maintain steroid-induced remission, allowing withdrawal of steroids. Treatment of severe, active rheumatoid arthritis, severe psoriasis in patients in whom conventional therapy is inappropriate or ineffective and Sandimmun Neoral is indicated in patients with severe atopic dermatitis when systemic therapy is required.
Place of Origin
The daily doses of Sandimmun Neoral should always be given in 2 divided doses. Because of considerable inter- and intraindividual variations in absorption and elimination and the possibility of pharmacokinetic drug interactions (see Interactions), doses should be titrated individually according to clinical response and tolerability.
Instructions for Use and Handling:
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