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For the treatment of hypertension, may be used alone or in combination with other antihypertensives, including diureticsHypertensive Patients with Left Ventricular Hypertrophy
- Decreases the risk of cardiovascular morbidity and mortality as measured by the combined incidence of cardiovascular death, stroke, and myocardial infarction in hypertensive patients with left ventricular hypertrophyHeart Failure
- Heart failure in patients who cannot tolerate an ACE inhibitorNephropathy in Type 2 Diabetic Patients
- For the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio &ge,300 mg/g) in patients with type 2 diabetes and a history of hypertensionDecreases the progression of nephropathy as measured by the occurrence of doubling serum creatinine, end stage renal disease (need for dialysis or renal transplantation), or death,Reduces proteinuria
Place of Origin
- The usual starting and maintenance dose is 50mg once daily for most patients.
- The maximal anti hypertensive effect is attained 3-6 weeks after initiation of therapy.
- Some patients may receive an additional benefit by increasing the dose to 100mg once daily (in the morning).
50mg Losartan Potassium
- Hypersensitivity to active substance or to any of the excipients
- Severe hepatic impairment
- Concominant use of angiotensin receptio antagonist including losartan or angiotensin converting enzyme inhibitors with allskiren in patients with type 2 diabetis
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