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Treatment of hypertensiion; for patients in whom combination therapy is appropriate.
Place of Origin
Usual Initial & Maintenance Adult Dose: 1 tablet of Losartan 50 mg + HCTZ 12.5 mg FDC once daily. Usual Initial & Maintenance Adult Dose: 1 tablet of Losartan 50 mg + HCTZ 12.5 mg FDC once daily. For patients who do not respond adequately, adjust to a maximum dose of:1 tablet of Losartan 100 mg + HCTZ 25 mg FDC daily or,
In general, the antihypertensive effect is attained within 3 weeks after initiation of therapy. Or, as prescribed by a physician.
Hypersensitivity to any component of this product. Therapy resistant hypokalemia or hypercalcemia. Severe hapatic impairment, cholestatis and biliary obstructive disorders. Refractory hyponatremia, Symptomatic hyperuricemia/gout. Pregnancy. Severe renal impairment (creatinine clearance <30ml/min). Anuria. Concomitant use with aliskiren in patients with diabetis mellitus or renal impairment (glomerular filtration rate (GFR) <60ml/min/1.73m2)