REMINDER: A doctor’s prescription is required to purchase this product. To avoid delay in delivery or cancellation of your order (before the item is SHIPPED); please email a copy of your prescription (.jpeg or .pdf file format) to OnlinePharmacy@smwatsons.com with your order number after Checkout. Our pharmacist will also get in touch with you to validate your prescription. Please be ready to show your original prescription upon claiming/delivery of your order.
Used for the suppression of inflammatory & allergic disorders; cerebral edema associated with malignancy; rheumatic disease; various skin & blood (eg; hemangioma & the Kasabach-Merritt syndrome) disorders; emergency management of acute idiopathic thrombocytopenic purpura (ITP) & management of chronic ITP.
Place of Origin
Should be taken with food.
Enhanced metabolism w/ CYP3A4 inducers eg; barbiturates; phenytoin; primidone; rifampicin; rifabutin; aminoglutethimide; carbamazepine & other drugs that stimulate hepatic metabolism. Decreased metabolism w/ CYP3A4 inhibitors eg; antifungals (itraconazole; ketoconazole); antiemetics (aprepitant; fosaprepitant); immunosuppressants (ciclosporin; cyclophosphamide; tacrolimus); macrolides (clarithromycin; erythromycin; troleandomycin); HIV-PIs; diltiazem; grapefruit juice. Inhibition or induction of hepatic clearance w/ CYP3A4 substrates eg; Ca antagonists (mibefradil); H2-receptor antagonists (cimetidine); contraceptives (ethinylestradiol/norethindrone) & Ca channel blockers (nifedipine; felodipine). Increased risk of hypokalemia w/ sympathomimetics eg; salbutamol; salmeterol; terbutaline; formoterol (at high doses of corticosteroids). Increased plasma conc w/ PIs (ie indinavir & ritonavir). Decreased absorption w/ antacids. Alterations in plasma protein-binding & metabolism w/ OCs & estrogen. Increased risk of GI effects eg; GI bleeding & ulceration w/ aspirin or other NSAIDs. Enhanced or diminished effects of anticoagulants. Hypokalemia w/ K-depleting diuretics (eg; furosemide & thiazide) or carbonic anhydrase inhibitors (eg; acetazolamide); amphotericin B. Reduced effect w/ mifepristone. Acute myopathy w/ anticholinergics eg; neuromuscular blockers (at high doses of corticosteroids). Increased blood glucose conc & impaired glucose tolerance w/ insulin & oral antidiabetics. Increased risk of arrhythmias due to hypokalemia w/ digitalis glycosides. Diminished response to toxoids & live or inactivated vaccines (prolonged use of corticosteroids).
Each tablet conatins 16 mg of methylprednisolone.
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