REMINDER: A doctor’s prescription is required to purchase this product. To avoid delay in delivery or cancellation of your order (before the item is SHIPPED); please email a copy of your prescription (.jpeg or .pdf file format) to OnlinePharmacy@watsons.com.ph with your order number after Checkout. Our pharmacist will also get in touch with you to validate your prescription. Please be ready to show your original prescription upon claiming/delivery of your order.
Primary hypercholesterolemia (type IIa including heterozygous familial hypercholesterolemia) or mixed dyslipidemia (type IIb) as an adjunct to diet when response to diet & other treatment is inadequate. Homozygous familial hypercholesterolemia as an adjunct to diet & other lipid-lowering treatments (eg, LDL apheresis) or if such treatments are not appropriate.
Individualized dosage. May be given at any time of the day. Adult Hypercholesterolemia Statin naive or patients switched from another HMG CoA reductase inhibitor Initially 5 or 10 mg once daily, may be adjusted dose after 4 wk. Severe hypercholesterolemia high risk CV risk Max: 40 mg. Childn & adolescent 10-17 yr (boys Tanner Stage ≥II & girls at least 1 yr post-menarche) Initially 5 mg daily. Usual dose: 5-20 mg once daily. Max: 20 mg. Elderly >70 yr Initially 5 mg. Asian & patient w/ predisposing factors to myopathy Initially 5 mg. Moderate renal impairment (CrCl <60 mL/min) Initially 5 mg.
May be taken with or without food.
Contraindications: Hypersensitivity. Active liver disease including unexplained, persistent elevations of serum transaminases & any serum transaminase elevation >3 times the upper limit of normal. Severe renal impairment; myopathy. Ciclosporin. Doses >40 mg in patients w/ predisposing factors for myopathy/rhabdomyolysis [moderate renal impairment (CrCl <60 mL/min), hypothyroidism, family history of muscular disorder & muscular toxicity w/ another HMG CoA reductase inhibitor or fibrate, alcohol abuse, Asian patients, fibrates]. Women of childbearing potential. Pregnancy & lactation.
Special Precautions: Proteinuria; myalgia, myopathy, rhabdomyolysis (rarely); interstitial lung disease (long-term therapy); risk of DM. Patients w/ predisposing factors for myopathy/rhabdomyolysis; history of liver disease; secondary hypercholesterolemia. Report immediately if inexplicable muscle pain, weakness or cramps occur, particularly if associated w/ malaise or fever. Not to be used in patients w/ acute, serious condition suggestive of myopathy or predisposing to development of renal failure secondary to rhabdomyolysis. Perform confirmatory test w/in 5-7 days if creatinine kinase (CK) levels is elevated; discontinue CK levels if markedly elevated (>5x ULN). Require liver function test prior to & 3 mth following treatment. Galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption. Concomitant use w/ gemfibrozil, ciclosporin, nicotinic acid, azoles, PIs & macrolides. Excessive alcohol consumption. Dizziness may occur when driving or operating machines. Asian patients. Pregnancy & lactation. Not recommended for childn <10 yr.
Choose between Home Delivery or Click & Collect!
Click & Collect
·FREE with no minimum purchase requirement
·Select the Watsons store nearest you
·Pay with credit card
·Expect your orders to be ready within:
·2-5 days for NCR (excluding Sundays)
·3-7 days for rest of Luzon and Visayas (excluding Sundays)
·4-8 days for Mindanao (excluding Sundays)
·Follow the instructions in the collection email and collect at your convenience—no need to queue!